Michigan's First-Round NFL Draft Selections
J.J. McCarthy, No. 26 overall selection of 2024 NFL Draft
(Through 2025 Draft)
| Year | Player, Position | Pick | Team |
| 1941 | Tom Harmon, B | 1 | Chicago Bears |
| 1941 | Forest Evashevski, B | 10 | Washington Redskins |
| 1942 | Bob Westfall, B | 5 | Detroit Lions |
| 1944 | Mervin Pregulman, G | 7 | Green Bay Packers |
| 1945 | Elroy Hirsch, B | 5 | Cleveland Rams |
| 1945 | Don Lund, B | 7 | Chicago Bears |
| 1947 | Elmer Madar, E | 1 | Miami Seahawks (AAFC) |
| 1947 | Bob Chappuis, B | 8 | Cleveland Browns (AAFC) |
| 1949 | Dan Dworsky, C | N/A | Los Angeles Dons (AAFC) |
| 1949 | Pete Elliott, B | N/A | Chicago Rockets (AAFC) |
| 1949 | Gene Derricotte, B | N/A | Cleveland Browns (AAFC) |
| 1957 | Ron Kramer, E | 4 | Green Bay Packers |
| 1958 | Jim Pace, B | 8 | San Francisco 49ers |
| 1960 | Don Deskins, T | N/A | Minneapolis (AFL) |
| 1960 | George Genyk, G | N/A | New York Titans (AFL) |
| 1966 | Tom Mack, OT | 2 | Los Angeles Rams |
| 1966 | Bill Yearby, T | 5 | New York Jets (AFL) |
| 1967 | Jim Detwiler, HB | 20 | Baltimore Colts |
| 1969 | Ron Johnson, RB | 20 | Cleveland Browns |
| 1972 | Thom Darden, DB | 18 | Cleveland Browns |
| 1972 | Mike Taylor, LB | 20 | New York Jets |
| 1973 | Paul Seymour, OT | 7 | Buffalo Bills |
| 1974 | Dave Gallagher, DL | 20 | Chicago Bears |
| 1975 | Dave Brown, DB | 26 | Pittsburgh Steelers |
| 1978 | Mike Kenn, OT | 13 | Atlanta Falcons |
| 1978 | John Anderson, LB | 26 | Green Bay Packers |
| 1979 | Jon Giesler, OT | 24 | Miami Dolphins |
| 1980 | Curtis Greer, DE | 6 | St. Louis Cardinals |
| 1981 | Mel Owens, LB | 9 | Los Angeles Rams |
| 1982 | Butch Woolfolk, RB | 18 | New York Giants |
| 1985 | Kevin Brooks, DE | 17 | Dallas Cowboys |
| 1987 | Jim Harbaugh, QB | 26 | Chicago Bears |
| 1991 | Jarrod Bunch, FB | 27 | New York Giants |
| 1992 | Desmond Howard, WR | 4 | Washington Redskins |
| 1993 | Steve Everitt, C | 14 | Cleveland Browns |
| 1994 | Derrick Alexander, WR | 29 | Cleveland Browns |
| 1995 | Tyrone Wheatley, RB | 17 | New York Giants |
| 1995 | Ty Law, DB | 23 | New England Patriots |
| 1995 | Trezelle Jenkins, OT | 31 | Kansas City Chiefs |
| 1996 | Tshimanga Biakabutuka, RB | 8 | Carolina Panthers |
| 1998 | Charles Woodson, CB | 4 | Oakland Raiders |
| 2001 | David Terrell, WR | 8 | Chicago Bears |
| 2001 | Steve Hutchinson, OG | 17 | Seattle Seahawks |
| 2001 | Jeff Backus, OT | 18 | Detroit Lions |
| 2004 | Chris Perry, RB | 26 | Cincinnati Bengals |
| 2005 | Braylon Edwards, WR | 3 | Cleveland Browns |
| 2005 | Marlin Jackson, CB | 29 | Indianapolis Colts |
| 2007 | Leon Hall, CB | 18 | Cincinnati Bengals |
| 2008 | Jake Long, OT | 1 | Miami Dolphins |
| 2010 | Brandon Graham, DE | 13 | Philadelphia Eagles |
| 2014 | Taylor Lewan, OL | 11 | Tennessee Titans |
| 2017 | Jabrill Peppers, S/LB | 25 | Cleveland Browns |
| 2017 | Taco Charlton, DE | 28 | Dallas Cowboys |
| 2019 | Devin Bush, LB | 10 | Pittsburgh Steelers |
| 2019 | Rashan Gary, DE/LB | 12 | Green Bay Packers |
| 2020 | Cesar Ruiz, C | 24 | New Orleans Saints |
| 2021 | Kwity Paye, DE | 21 | Indianapolis Colts |
| 2022 | Aidan Hutchinson, DL | 2 | Detroit Lions |
| 2022 | Daxton Hill, DB | 31 | Cincinnati Bengals |
| 2023 | Mazi Smith, DL | 26 | Dallas Cowboys |
| 2024 | J.J. McCarthy, QB | 26 | Minnesota Vikings |
| 2025 | Mason Graham, DT | 5 | Cleveland Browns |
| 2025 | Colston Loveland, TE | 10 | Denver Broncos |
| 2025 | Kenneth Grant, DT | 13 | Miami Dolphins |
